Īdvantages of natural gums in pharmaceutical science The design of novel drug delivery systems. Now a day’s extensive studies are being conductedįor finding the applicability of these natural excipients in Obtained from plants have diverse applications in drugĭelivery and they play different roles in dosage forms asīinders, disintegrants, emulsifying agents and suspending agents. Ones since they are chemically inert, nontoxic, less expensive,īiodegradable and widely available. These natural excipients have advantages over synthetic In to three types, based on their nature of origin as Helps in getting safe and effective dosage form suitable forĪdministration to patients. Not interfere with physical, chemical and pharmacologicalĮffects of the active ingredients but they assist in gettingĭesired pharmacological effect from the dosage forms and
Mankind and improves the health of all living things eitherĭirectly or indirectly. Nature has provided a wide variety of materials to help Mucuna Gum Rheological Properties Introduction Physico-chemical Properties Bhara gum Grewia gum
The bacterial and fungal counts were within limits and pathogenic microorganisms were absent and acute toxicity studies indicated that these gumswere safe to use. The gums exhibiting non-Newtonian plastic flow, this indicates the gelling behavior and confirms their suitability in the development of controlled release delivery systems.įTIR and DSC studies were carried out for characterization of gums and results indicated that there was no change in the absorption spectra. The natural polymers which were characterized in the present research work have showed good flow properties and suitable physico chemical properties like low moisture content which enables low chance of microbial growth, high swelling index indicates high swellability and goodwater retention capacity there by enhanced permeation of drug for longer periods of time. Many naturally available polymers were being investigated for their applications in the design of sustained drug delivery systems. The main concern of the present investigation is to provide new sustained release excipient which, when incorporated into a final product, produces controlled release of active ingredient over an extended period of 12hrs or more when the dosage form is exposed to G.I fluids in gastric environment.
0 kommentar(er)
